Hypercalcemia
  1. What is it? Answer

  2. What causes it? Answer

  3. How many causes are there?Answer

  4. What are the risk factors? Answer

  5. What's normal? Answer

  6. How is it diagnosed? Answer

  7. What are the symptoms? Answer

  8. What are the signs? Answer

  9. What are the clinical findings? Answer

  10. What are the lab or investigation findings? Answer

  11. What is the treatment? Answer

  12. What are the workable treatment options? Answer

  13. How could this be prevented? Answer


Hypercalcemia Causes

What causes it?
Overactive parathyroid glands
Cancer
Calcium supplements and hypercalcemia
Vitamin D and hypercalcemia
Vitamin A and hypercalcemia
Medications that cause hypercalcemia
Genetics and hypercalcemia

The possible causes of high calcium levels include more than 25 diseases, as well as some medications, supplements, genes, and lifestyle factors.

Cancer

The most common cancer types that cause hypercalcemia include:

Lung cancer
Kidney cancer
Breast cancer
Multiple myeloma (a blood cancer that starts in the bone marrow)

Hypercalcemia from cancer can be hard to manage. It helps to treat your cancer. But you may need drugs to slow the release of calcium from your bones, including:

Bisphosphonates, given through your veins
Denosumab (Prolia, Xgeva), given as a shot

Medications that cause hypercalcemia

Medications that might cause or worsen high calcium levels include:

Blood pressure drugs, such as thiazide diuretics, which can lower the amount of calcium that leaves your body when you pee Lithium, which might affect your parathyroid glands and the amount of PTH they make

Mild

Most cases of hypercalcemia aren’t life-threatening and many people don’t have any symptoms.

Ssevere

Ssevere hypercalcemia can cause more serious problems, including:

Kidney failure.
Abnormal heart rhythm (arrhythmia).
Confusion.
Coma.

What is the treatment?
If your calcium levels are very high, for any reason, you'll need to go to the hospital to get fluids and medicine called diuretics through your veins. This can treat hypercalcemia quickly.